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DrugMAP: molecular atlas and pharma-information of all drugs (DrugMAP)

The efficacy and safety of drugs are widely known to be determined by their interactions with multiple molecules of pharmacological importance, and it is therefore essential to systematically depict the molecular atlas and pharma-information of studied drugs. However, our understanding of such information is neither comprehensive nor precise, which necessitates the construction of a new database providing a network containing a large number of drugs and their interacting molecules. Here, a new database describing the molecular atlas and pharma-information of drugs (DrugMAP) was therefore constructed. It provides a comprehensive list of interacting molecules for >30 000 drugs/drug candidates, gives the differential expression patterns for >5000 interacting molecules among different disease sites, ADME (absorption, distribution, metabolism and excretion)-relevant organs and physiological tissues, and weaves a comprehensive and precise network containing >200 000 interactions among drugs and molecules. With the great efforts made to clarify the complex mechanism underlying drug pharmacokinetics and pharmacodynamics and rapidly emerging interests in artificial intelligence (AI)-based network analyses, DrugMAP is expected to become an indispensable supplement to existing databases to facilitate drug discovery. It is now fully and freely accessible at: https://idrblab.org/drugmap/.

Website
Record in FAIRsharing (doi:10.25504/FAIRsharing.27137a)
Subjects: Drug Development, Drug Discovery, Drug Repositioning

Documentation, events and training

bio.tools API and tool documentation

DrugMAP (same homepage)

What is known per question

The questions of the decision tree, with what FAIRsharing says about this repository. ✓ supported, ✗ excluded, ? not known.

What kind of data do you want to archive?

? Spectra
? Crystal structures
? Computational chemistry
? Catalysis
? Compounds and reactions
? Bioassays and chemical biology
? Materials and polymers
? Images and microscopy
? Something else

Subjects: Drug Development; Drug Discovery; Drug Repositioning

Domains: Approved drug; Drug name; Drug report; Drug structure; FDA approved drug; drug; drug interaction

Does the journal or publisher you publish with require or recommend a repository?

? Yes
? No
? I do not know

FAIRsharing has no information on this.

Which discipline does your data belong to?

FAIRsharing has no information on this.

Which publisher?

FAIRsharing has no information on this.

Does your funder have requirements for where data is archived?

? Yes
? No
? I do not know

FAIRsharing has no information on this.

Which funder?

FAIRsharing has no information on this.

Does your institution offer a data repository?

? Yes
? No
? I do not know

FAIRsharing has no information on this.

Which institution?

FAIRsharing has no information on this.

Can your data be shared openly?

✓ Yes, openly available
? Yes, after an embargo
✗ Only with restrictions

Data access: open

Data deposition: not applicable

How large is your dataset?

? Less than 1 GB
? 1 GB to 50 GB
? 50 GB to 1 TB
? More than 1 TB

FAIRsharing has no information on this.

Why can the data not be open?

? It contains personal data
? Commercial or intellectual property reasons
? Safety or security concerns
? A data sharing agreement limits it

FAIRsharing has no information on this.

Under which license do you want to share the data?

? CC0 / public domain
? CC BY
? Another open license
? Not decided yet

FAIRsharing has no information on this.

Do you need a persistent identifier, such as a DOI, for citing the data?

? Yes, a DOI
? Any persistent identifier will do
? No

FAIRsharing has no information on this.

Must the data be stored in a specific region?

✗ In the European Union
? In a specific country
✓ No preference

Country: China

Must archiving be free of charge?

? Yes, free only
? A fee is fine

FAIRsharing has no information on this.

Which country?

? not known for the list ✗ excludes 15

Country: China