Repository · FAIRsharing
Molecular Glue and Ternary binding database (MGTbind)
Compounds and reactionsBioassays and chemical biologyImages and microscopy
MGTbind database contains 3,093 manually curated MGs with their chemical structures and physicochemical properties, along with 3,924 ternary interactions with bioactivity measurements (e.g. degradation capacities for MG degraders, in vitro biochemical activities and cellular activities). Hierarchical binding affinity is also collected to enable exploring of cooperative binding mechanisms. Ternary complex structural data are systematically integrated, either from the Protein Data Bank or generated by AlphaFold 3. All of them can be intuitively analyzed and visualized along with various predicted metrics. A fully functional and user-friendly web interface that allows global search and smooth browsing is provided and is freely accessible at https://mgtbind.pkumdl.cn.
- Website
- Record in FAIRsharing
- Subjects: Bioinformatics, Biology, Chemical Biology, Chemistry, Computational Biology, Structural Biology
What is known per question
The questions of the decision tree, with what FAIRsharing says about this repository. ✓ supported, ✗ excluded, ? not known. Your own answers are marked.
What kind of data do you want to archive?
- ? Spectra
- ? Crystal structures
- ? Computational chemistry
- ? Catalysis
- ✓ Compounds and reactions
- ✓ Bioassays and chemical biology
- ? Materials and polymers
- ✓ Images and microscopy
- ? Something else
Subjects: Bioinformatics; Biology; Chemical Biology; Chemistry; Computational Biology; Structural Biology
Domains: Chemical structure image; Drug structure; Protein structure; Protein-Protein Interaction; Structure; protein
Does the journal or publisher you publish with require or recommend a repository?
- ? Yes
- ? No
- ? I do not know
FAIRsharing has no information on this.
Which discipline does your data belong to?
FAIRsharing has no information on this.
Which publisher?
FAIRsharing has no information on this.
Does your funder have requirements for where data is archived?
- ? Yes
- ? No
- ? I do not know
FAIRsharing has no information on this.
Which funder?
FAIRsharing has no information on this.
Does your institution offer a data repository?
- ? Yes
- ? No
- ? I do not know
FAIRsharing has no information on this.
Which institution?
FAIRsharing has no information on this.
Can your data be shared openly?
- ✓ Yes, openly available
- ? Yes, after an embargo
- ✗ Only with restrictions
Data access: open
Data deposition: not applicable
How large is your dataset?
- ? Less than 1 GB
- ? 1 GB to 50 GB
- ? 50 GB to 1 TB
- ? More than 1 TB
FAIRsharing has no information on this.
Why can the data not be open?
- ? It contains personal data
- ? Commercial or intellectual property reasons
- ? Safety or security concerns
- ? A data sharing agreement limits it
FAIRsharing has no information on this.
Under which license do you want to share the data?
- ? CC0 / public domain
- ? CC BY
- ? Another open license
- ? Not decided yet
FAIRsharing has no information on this.
Do you need a persistent identifier, such as a DOI, for citing the data?
- ? Yes, a DOI
- ? Any persistent identifier will do
- ? No
FAIRsharing has no information on this.
Must the data be stored in a specific region?
- ✗ In the European Union
- ? In a specific country
- ✓ No preference
Country: China
Must archiving be free of charge?
- ? Yes, free only
- ? A fee is fine
FAIRsharing has no information on this.
Which country?
? not known for the list ✗ excludes 15
Country: China